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1. The activity of myosin II motor and the volume of actin filament cooperatively regulate cytokinesis of | |||
Yang Fang,An Meiwen,Li Xiaona,Wang Li | |||
Biology 25 March 2010 | |||
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Abstract:The coordination of different cytoskeletons is an important factor in maintaining normal physiological and biochemical characteristics. In this study, normal rat kidney (NRK) cells in cytokinesis were treated with cytoskeleton inhibitors including cytochalasin D (CD), colchicine (COLC) oblebbistatin (myosin II motor activity inhibitor ). These inhibitors were released at the whole region and the localized region in two phases of cytokinesis. The influences were analyzed. It was showed that the roles of cytoskeleton inhibitors to cytokinesis were complex, for different treatment of inhibiotors corresponding to different results. The study indicated that the interaction in actin and the activity of myosin II motor is vital to cell shape and operation in every stages of cytokinesis. | |||
TO cite this article:Yang Fang,An Meiwen,Li Xiaona, et al. The activity of myosin II motor and the volume of actin filament cooperatively regulate cytokinesis of [OL].[25 March 2010] http://en.paper.edu.cn/en_releasepaper/content/41129 |
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