Authentication email has already been sent, please check your email box: and activate it as soon as possible.
You can login to My Profile and manage your email alerts.
If you haven’t received the email, please:
|
|
There are 181 papers published in subject: since this site started. |
Select Subject |
Select/Unselect all | For Selected Papers |
Saved Papers
Please enter a name for this paper to be shown in your personalized Saved Papers list
|
1. Image Reconstruction for Fan Beam X-Ray Tomography Using General Hankel Transform Pair (2) | |||
Zhao Shuangren | |||
Basic Medicine 27 June 2006 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:A new transform pair has been introduced for the fan-beam image reconstruction[10]. This new integral transform plays the same role as the Hankel ( Fourier Bessel) transform in the parallel beam case and includes the Hankel transform as a special case. In this paper we develop this method for the equal-angle fan beam geometry. We call this new pair the General Hankel transform which gives transform and inverse transform from an object function f(r,beta) to fan beam projections R_beta(gamma). One member of the pair can be used to calculate projection data for simulation; the other can be used as an algorithm for fan beam reconstruction without interpolation in polar coordinates. Compared with other algorithms for fan beam reconstruction the general Hankel transform method is especially useful when f(r,beta) the image to be reconstructed, has only low frequencies in the theta angle direction and only few projections are available. | |||
TO cite this article:Zhao Shuangren . Image Reconstruction for Fan Beam X-Ray Tomography Using General Hankel Transform Pair (2)[OL].[27 June 2006] http://en.paper.edu.cn/en_releasepaper/content/7335 |
2. Data analysis of HLA-A*0201 bound peptide nonamers in PDB | |||
Zhang Ruxiang,Huang Qinghai,Zhang Jianqiong,Xie Wei | |||
Basic Medicine 18 May 2006 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:HLA structural data were downloaded from PDB. All data were filtered by programming and were managed in the Visual FoxPro (VFP). With Biopolymer module of InsigtII software, hydrogen atoms were added to filtered molecules. Then, the program was utilized to analyze distances of every two Cα atoms of peptide nonamers and amino acid residues of HLA involved within a different distance around 26 peptide nonamers respectively. There were 26 HLA-A*0201 complexes with peptide nonamers in PDB. The position 2(P2) of 21 peptides was Leu. Meanwhile, P9 was either Leu or Val mostly (25/26). The mean number of H-bond between P1 and molecule HLA-A*0201 was 1.86, while those at P2 and P9 were 1.81, 1.95 respectively. By method of moment, some distances of two Cα atoms appeared normal school. Some amino acid residues of HLA, such as Tyr7, Glu63, Lys66, His70, Thr73, Ser77, Leu81, Tyr99, Thr143, Trp147 and Tyr171, appeared above 90% within a distance of 0.25 nm around peptide nonamers. P1 maybe is anchoring residue, just like P2 and P9. Distances of two Cα atoms of peptide nonamers can be utilized to check whether the structure of peptide is reasonable after molecular docking. Some high frequency residues can be applied to adjust binding subset for docking | |||
TO cite this article:Zhang Ruxiang,Huang Qinghai,Zhang Jianqiong, et al. Data analysis of HLA-A*0201 bound peptide nonamers in PDB[OL].[18 May 2006] http://en.paper.edu.cn/en_releasepaper/content/6680 |
3. Image Reconstruction for Fan Beam X-Ray Tomography Using General Hankel Transform Pair (1) | |||
Zhao Shuangren | |||
Basic Medicine 24 April 2006 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:A new integral transform pair has been introduced for the reconstruction of slices from fan beam projection data. This integral transform plays the same role as the Hankel transform (or Fourier Bessel transform) in the parallel beam case and includes the Hankel transform as a special case. The relations between the new integral transform and the Hankel transform pair are derived and the implementation of the algorithm is described. Memory space requirements and speed of the transform are discussed and the advantage of precalculations are mentioned. The transform pair is especially useful in case the two dimensional object slice to be reconstructed has only few low frequency components in the azimutal direction. Furthermore the method is capable of treating the case where non analytic a priori information is to be taken into account. In this case projections into the measurement directions are performed and the differences between these projection data and the measured data are reconstructed in order to improve the object data. Alternating transformations between projection and object space are efficient and fast. Finally some results of simulations including the influence of noise are shown and possible applications of the method are discussed. | |||
TO cite this article:Zhao Shuangren . Image Reconstruction for Fan Beam X-Ray Tomography Using General Hankel Transform Pair (1)[OL].[24 April 2006] http://en.paper.edu.cn/en_releasepaper/content/6367 |
4. The up-regulated expression of hALP gene by genotoxic agents confers cellular resistance to DNA damage | |||
Liu Haijing ,Ling Yun,Lin Hou,Zhang Bo | |||
Basic Medicine 17 March 2006 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:Objective: To confirm the response of hALP, a telomerase regulation-associated gene, to DNA damage. Methods: HeLa and Hep2 cells were respectively treated by genotoxic agents of hydrogen peroxide (H2O2) or cisplatin. The induced expression of hALP was measured by semi-quantitative RT-PCR and immunofluorescence. The transcriptional activity of hALP promoter was estimated by luciferase reporter assay. The cell survivor in the presence of genotoxic agents was analyzed by MTT method. Results: The level of hALP mRNA could be increased when treated by 0.2 ~ 1.6 mmol/L H2O2 and reach a peak in the concentration of 0.4 mmol/L. The induction could be observed after 6 h at the presence of 0.4 mmol/L H2O2 and hold high level for 36 h. Similarly, cisplatin induced hALP mRNA expression both in dose- or time-dependent. hALP protein was increased in immunofluorescent staining and concentrated in cellular nuclei with the treatment of H2O2 or cisplatin, which also stimulated the transcriptional activity of hALP promoter in luciferase assays through its upstream -705 ~ +20 nt region. On the other hand, HeLa cells expressing sense hALP gene could grow continuously in the present of 0.4 mmol/L H2O2 or 0.5µmol/L cisplatin, while cells with anti-sense hALP or control cells were slow in growth. Conclusions: The expression of hALP gene could be up-regulated by DNA damage through activating transcription of its promoter, and increase cellular resistance to genotoxic agents. | |||
TO cite this article:Liu Haijing ,Ling Yun,Lin Hou, et al. The up-regulated expression of hALP gene by genotoxic agents confers cellular resistance to DNA damage[OL].[17 March 2006] http://en.paper.edu.cn/en_releasepaper/content/5764 |
5. Effect of Glutamine on the Expression of grp75 in PC12 Cells under Glucose Deprivation | |||
Liu Wen,Liu Xiaoyu,Zhang Yan ,Yang Ling,Zuo Ji | |||
Basic Medicine 17 March 2006 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:To investigate the effect of glutamine(Gln) on the expression of grp75 and the protective effect in PC12 cell line under glucose deprivation (GD), grp75 expression of PC12 cell with administration of Gln was analyzed by western blot and immunocytochemistry, and the change of mRNA level of grp75 was detected by RT-PCR. The cell viability (survival and apoptosis rate) and mitochondria function (mitochondria transmembrane potential) were also observed by MTT method and flow cytometry. The results showed that Gln could enhance the expression of grp75 at both a protein level and a mRNA level. The cell treated with Gln, its survival rate increased and apoptosis rate decreased under glucose deprivation. These data suggested that glutamine can protect cells from the injury induced by glucose deprivation through the expression of grp75. | |||
TO cite this article:Liu Wen,Liu Xiaoyu,Zhang Yan , et al. Effect of Glutamine on the Expression of grp75 in PC12 Cells under Glucose Deprivation[OL].[17 March 2006] http://en.paper.edu.cn/en_releasepaper/content/5761 |
6. Neonatal Murine Keratinocytes Split Express CD80/CD86 upon Culture | |||
LeiJianjun,ChengJingqiu,LiYouping,LiShengfu,ZhangLi,KeNengwen | |||
Basic Medicine 28 December 2005 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:It was previously thought that keratinocytes did not express the CD80 and CD86 which provide the most important costimulatory signals for the antigen-specific T-cell activation.The cultured keratinocytes allografts were initially accepted,but eventually,allgrafted donor cells were gradually replaced by recipient cells.The precise mechanisms are not very clear.In this study,neonatal murine keratinocytes were cultured for 7 days,the results of flowcytometry and confocal microscopy showed that CD80 could be detected on keratinocytes,whileCD86 could not be detected all the time.RT-PCR analysis confirmed this result.The expression level of the CD80 mRNA amplified significantly from day1 to day 7,as expression of the control B-actin,but CD86 was not detected.Mixed Lymphocyte Reaction(MLR) showed that keratinocytes cultured with 10% serum for 7d stimulated effectively allogeneic rather than syngeneic T cell proliferation.This study demonstrated for the first time that co-stimulatory molecule CD80 can be expressed onkeratinocytes invitro.These data provided an alternative explanation for the ultimate rejection of allogeneic keratinocytes in which keratinocytes act as antigen-presenting cells. | |||
TO cite this article:LeiJianjun,ChengJingqiu,LiYouping, et al. Neonatal Murine Keratinocytes Split Express CD80/CD86 upon Culture[OL].[28 December 2005] http://en.paper.edu.cn/en_releasepaper/content/4704 |
7. Effects of the cultured Cordyceps exopolysaccharide (EPS) on some parameters of mouse immune function in vivo and in vitro1 | |||
Weiyun Zhang,Jinyu Yang,Jiaping Chen,Jing Li,Yi Zheng | |||
Basic Medicine 14 December 2005 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:The Cordyceps fungi (CSG1) were cultured and the exopolysaccharide (EPS) was prepared from the culture supernatant. In vivo experiment, ICR mice were treated with three different doses of EPS for seven days. In vitro study, macrophage, spleen and thymus lymphocytes were incubated in the presence of five different concentrations of EPS. The phagocytosis of peritoneal macrophage was determined by neutral red uptake test and the proliferation abilities of spleen and thymus lymphocyte were studied with MTT method. The results of in vivo study illustrated that the macrophage neutral red uptake ability of mice was significantly enhanced by three different doses of EPS (p<0.001) and spleen lymphocyte’s proliferation was elevated at the dose of 60 mg/kg (p<0.01). However, thymus lymphocyte proliferation did not show significant variation compared with the control mice after seven day’s EPS treatment. In vitro study, EPS not only significantly elevated the phagocytosis of peritoneal macrophage in the concentration of 50 and 100 mg/L (p<0.05), but also significantly increased the proliferation abilities of spleen and thymus lymphocytes in 100 mg/L (p<0.001 and p<0.05, respectively). These results suggest that EPS has an immunomodulatory activity on mouse macrophages and lymphocytes, and this ability might be useful for application to assist treating some diseases such as cancers. | |||
TO cite this article:Weiyun Zhang,Jinyu Yang,Jiaping Chen, et al. Effects of the cultured Cordyceps exopolysaccharide (EPS) on some parameters of mouse immune function in vivo and in vitro1 [OL].[14 December 2005] http://en.paper.edu.cn/en_releasepaper/content/4362 |
8. The effect of reference choices on the spatio-temporal analysis of brain evoked potentials: the use of infinite reference | |||
Dezhong Yao,Li Wang,Lars Arendt-Nelsen,Andrew C. N Chen | |||
Basic Medicine 12 December 2005 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:Reference is a very virtual issue in EEG and ERP. Understanding the difference of various references will make the applications more confident. In this work, somatosensory evoked potential (SEP) with stimulation on the right hand was studied. The SEP spatio-temporal analysis was conducted comparatively on five references, left mastoid (contralateral mastoid reference, CM), right mastoid (ipsilateral mastoid reference, IM), linked mastoids (LM), average reference (AR) and the infinity reference (IR) newly proposed in 2001. Among the five, CM is the one used in actual recordings, the other four are obtained by off-line re-referencing. The comparison is conducted on four selected components (P30ms, P40ms, N90ms and P230ms) in both temporal and spatial aspects. The results show that references may have a distinct influence on the amplitudes of the scalp potentials, with relative error at some electrodes larger than 200%, and for some electrodes it may even change the polarity. Pair-wise multiple comparison (Tukey test) shows that the differences of Peak values among various references are very significant (P<0.001) between AR and CM\\IM\\LM, and significant (P<0.05) between IR and CM\\IM\\AR for component P230ms, the amplitude value order is CM/IM 刣 LM>IR>AR. The two-ways (the five References vs. the four Peaks) repeated measures ANOVA test shows the effect of different references depends on various components, there is a statistically significant interaction between Reference and the Peak (P = <0.001). While for the spatial map of the potential amplitude, references will not affect the amplitude map shape if the color-bar is selected automatically, but if a fixed color-bar is chosen for data of various references, they may show some differences. These results mean a common reference is important for producing a comparable result between labs. As IR is theoretically a constant reference, we recommend it as the common choice in the future. | |||
TO cite this article:Dezhong Yao,Li Wang,Lars Arendt-Nelsen, et al. The effect of reference choices on the spatio-temporal analysis of brain evoked potentials: the use of infinite reference[OL].[12 December 2005] http://en.paper.edu.cn/en_releasepaper/content/4226 |
9. Two dictionaries Matching Pursuit for sparse decomposition of signals | |||
Peng Xu,Dezhong Yao | |||
Basic Medicine 08 December 2005 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:Signal may be decomposed sparsely and power-focally in an over-complete dictionary with Matching Pursuit (MP). In this paper, proposed is a modified MP method named two dictionaries MP to decompose signal more sparsely. In the iteration procedure of the two dictionaries MP, the over-complete dictionary is classified into two separate dictionaries with the selected and unselected atoms, and in each iteration, the algorithm was designed to have more chances than the original MP to choose the atom in the selected atom dictionary as the optimal atom by a simulate annealing threshold function, thus the algorithm avails for a more sparse decomposition. The decomposition results for a cosine-modulated exponential signal and an actual speech signal showed that the proposed two dictionaries MP could decompose signal more sparsely. | |||
TO cite this article:Peng Xu,Dezhong Yao. Two dictionaries Matching Pursuit for sparse decomposition of signals[OL].[ 8 December 2005] http://en.paper.edu.cn/en_releasepaper/content/4180 |
10. Effects of alpha fetoprotein on escape of Bel 7402 cells from attack of lymphocytes | |||
Mengsen Li | |||
Basic Medicine 11 April 2005 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:nvolvement of AFP against apoptosis of tumor cell has been implicated in its evasion of immune surveillance. However, the molecular events of immune escape mechanisms are still unknown. The major observations reported here relate to a possible mechanism by which heptoloma Bel 7402 cells escape immune surveillance in vitro. Western blotting and a well-characterized cofocal scanning image were performed to analyze the expression of Fas/FasL and caspase-3 in co-cultured Bel 7402 and Jurkat cells. After co-culture with Jurkat cells, up-regulated Fas and reduced FasL expression could be observed. Treatment with AFP could remarkably inhibit the elevated Fas and, whereas, induce the FasL expression in co-cultured Bel 7402 cells. Cells co-culture could induce the expression of caspase-3 in both cells line. The elevated caspase-3 in Bel 7402 cells was abolished following the treatment of AFP. The expression of caspase-3 was elevated in co-cultured Jurkat cells treated with AFP. No detectable | |||
TO cite this article:Mengsen Li. Effects of alpha fetoprotein on escape of Bel 7402 cells from attack of lymphocytes[OL].[11 April 2005] http://en.paper.edu.cn/en_releasepaper/content/1829 |
Select/Unselect all | For Selected Papers |
Saved Papers
Please enter a name for this paper to be shown in your personalized Saved Papers list
|
|
About Sciencepaper Online | Privacy Policy | Terms & Conditions | Contact Us
© 2003-2012 Sciencepaper Online. unless otherwise stated