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1. The dose distribution detection design of fragments for heavy ions therapy | |||
Xinjian Tan | |||
Basic Medicine 24 March 2008 | |||
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Abstract:The charged ions have been used in tumor therapy instead of conventional radiation therapy since 1970’s mainly as its favorable depth profile of the relative biological effectiveness (RBE). However, the projectiles fragments produced inside patient’s body reach a region beyond the range of the primary particles, and cause needless exposure, known as ‘fragment tail’, which spoil the therapy effect seriously. The production of fragments is one of the most crucial, but not yet perfectly understood, problems to be considered when planning for the utilization of heavy ions therapy, and there is no detailed experimental description about the dose distribution it caused until now. In this paper, we introduce a method of detecting the light fragments briefly with the aim of giving a feasible way to measure the spatial dose distribution behind the Bragg peak or Spread out Bragg peak (SOBP) using the CR-39 solid state nuclear track detector, the HSP-1000 microscope system and the PitFit track measurement analysis software. | |||
TO cite this article:Xinjian Tan. The dose distribution detection design of fragments for heavy ions therapy[OL].[24 March 2008] http://en.paper.edu.cn/en_releasepaper/content/19622 |
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