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The activity of myosin II motor and the volume of actin filament cooperatively regulate cytokinesis of
Yang Fang *,An Meiwen,Li Xiaona,Wang Li
Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology
*Correspondence author
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Funding: none
Opened online:25 March 2010
Accepted by: none
Citation: Yang Fang,An Meiwen,Li Xiaona.The activity of myosin II motor and the volume of actin filament cooperatively regulate cytokinesis of [OL]. [25 March 2010] http://en.paper.edu.cn/en_releasepaper/content/41129
 
 
The coordination of different cytoskeletons is an important factor in maintaining normal physiological and biochemical characteristics. In this study, normal rat kidney (NRK) cells in cytokinesis were treated with cytoskeleton inhibitors including cytochalasin D (CD), colchicine (COLC) oblebbistatin (myosin II motor activity inhibitor ). These inhibitors were released at the whole region and the localized region in two phases of cytokinesis. The influences were analyzed. It was showed that the roles of cytoskeleton inhibitors to cytokinesis were complex, for different treatment of inhibiotors corresponding to different results. The study indicated that the interaction in actin and the activity of myosin II motor is vital to cell shape and operation in every stages of cytokinesis.
Keywords:actin;myosin;microtubule;motor activity
 
 
 

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