Home > Papers

 
 
Hibernation effects on muscle morphological characteristics and fiber type composition in dauria ground squirrels (Spermophilus dauricus
GAO Yunfang 1 * #,WANG Jun 2,WANG Huiping 3,FENG Ban 3,DANG Kai 3,WANG Qi 3,Helmut G. Hinghofer-Szalkay 4
1.Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education
2.Department of Obstetrics and Gynecology, Tangdu Hospital, Forth Military Medical University, Xi'an 710038, China
3.Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an, 710069, China
4.Institute of Adaptive and Spaceflight Physiology, Wormgasse 9, A-8010 Graz, Austria
*Correspondence author
#Submitted by
Subject:
Funding: National Nature Science Foundation of China （No.No. 30770273), Key Laboratory foundation of Resource Biology and Biotechnology in Western China）
Opened online:19 January 2011
Accepted by: none
Citation: GAO Yunfang,WANG Jun,WANG Huiping.Hibernation effects on muscle morphological characteristics and fiber type composition in dauria ground squirrels (Spermophilus dauricus[OL]. [19 January 2011] http://en.paper.edu.cn/en_releasepaper/content/4401424
 
 
Aim: We studied effects of hibernation on extensor digitorum longus (EDL) weight, fiber cross-sectional area (CSA), fiber type distribution, and myosin ATPase activity in dauria ground squirrels (Spermophilus dauricus). Methods: Muscle mass, fiber CSA (video analysis), fiber type, and myosin ATPase activity (Ca2+-ATPase) were measured before and after 1 and 2 months of hibernation, and 2-4 days after arousal in different groups of ground squirrels. Results: Compared with pre-hibernation, body weight decreased by about 10% per hibernation month and muscle wet weight was not altered. However, muscle-to-body weight ratio increased significantly. Both type I and type II fiber CSA increased by about 8% during hibernation, with no obvious influence of hibernation duration. Hibernation caused a slight but significant decrease in both ATPase activity and the percentage of type II fibers. 2-4 days after arousal, both fiber CSA and fiber type distribution returned to pre-hibernation levels. No type II fiber sub-type can be identified in dauria ground squirrel EDL samples. Conclusion: We report first data on EDL fiber type distribution and hibernation effects in dauria ground squirrels. EDL did not show any sign of atrophy over the 3-month winter dormancy. These results suggest that a potential mechanism exists in hibernators that would allow them to prevent muscle atrophy for the prolonged disuse.
Keywords:Dauria ground squirrels;extensor digitorum longus;myosin ATPase;hibernation
 
 
 

For this paper
  • ● PDF (0B)
  • ● Revision 0 　　
  • ● Print this paper
  • ● Recommend this paper to a friend
  • ● Add to my favorite list

    Saved Papers

    Please enter a name for this paper to be shown in your personalized Saved Papers list

Tags
Add yours

Related Papers

Statistics
PDF Downloaded 290
Bookmarked 0
Recommend 5
Comments Array
Submit your papers