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Objective: To investigate the effectiveness of endoscopic surgery for recurrent sinonasal inverted papilloma and evaluate the recurrence rates of endoscopic and open resection at a single institution. Methods: Retrospective study was performed on 21 patients underwent operation in our department with histopathologically confirmed recurrent sinonasal inverted papilloma from January 1990 to January 2005. According to the Krouse staging system, the 21 recurrent cases were categorized into 1 case of Stage 1 (5%), 18 cases of Stage 2 (85%), 2 cases of Stage 3 (10%), and 0 case of Stage 4 (0%). There were 7 cases (33%) underwent endoscopic resection and 14 cases (67%) received open resection. Results: Of 21 recurrent patients who underwent resection, 4 patients (19%) were found to recur. The average time to recurrence was 28 months. The recurrence rates of patients with Stage 1, Stage 2 and Stage 3 were 0%, 17% and 50%, respectively (p<0.05). Recurrence was observed in 1 case (14%) in the endoscopic group and 3 cases (21%) in the open group (p>0.05). There was statistical difference in recurrence rates between Stage 1 and Stage 2 in endoscopic group (p<0.05) and between Stage 2 and Stage 3 in open group (p<0.05), respectively. There was no significant difference in recurrence rates between endoscopic and open group in comparable Stage 2 (p>0.05). Conclusion: Endoscopic and open approaches are both available to achieve radical excision of the recurrent sinonasal inverted papilloma with similar rates of recurrence. The risk of recurrence is likely related to the Krouse stage of the tumor, with more aggressive tumors having a higher propensity for recurrence. Endoscopic surgery is an effective treatment for recurrent sinonasal inverted papilloma. |
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Keywords:Inverted papilloma; Endoscopic surgery; Staging; Recurrence rate |
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