Home > Papers

 
 
Origin, evolution and functional diversity of bHLH gene family: insights from comparative genomics and interactomics
Min Mingwei,Xu Junli,Yizheng Zhang,Yue Bisong,Li Xiao * #
College of Life Sciences, Sichuan University, Chengdu, People’s Republic of China
*Correspondence author
#Submitted by
Subject:
Funding: Doctoral Doctoral Fund of Ministry of Education of China （No.Grant No. 00806101013)）, the National Science and Technology Major Project of the Ministry of Science and Technology of China （No.Grant No. 2009ZX10005-020）
Opened online: 6 January 2012
Accepted by: none
Citation: Min Mingwei,Xu Junli,Yizheng Zhang.Origin, evolution and functional diversity of bHLH gene family: insights from comparative genomics and interactomics[OL]. [ 6 January 2012] http://en.paper.edu.cn/en_releasepaper/content/4458487
 
 
The basic helix-loop-helix (bHLH) proteins make up of a complex multigene family of transcription factors that play the important roles in many biological processes. Although much effort has been made on their functional roles, their evolutionary origin and functional diversity remain to be clarified. In this study, we compared genomes and interactomes of bHLH gene families from model organisms such as human, fly, worm, yeast and Arabidopsis to shed light on origin, evolution and functional diversity of this gene family, inferring that bHLHs might origin in prokaryotes and undergo divergence in different linage because of distinct evolutionary force.
Keywords:bHLH; evolution; genomics; interactomics
 
 
 

For this paper
  • ● PDF (0B)
  • ● Revision 0 　　
  • ● Print this paper
  • ● Recommend this paper to a friend
  • ● Add to my favorite list

    Saved Papers

    Please enter a name for this paper to be shown in your personalized Saved Papers list

Tags
Add yours

Related Papers

Statistics
PDF Downloaded 299
Bookmarked 0
Recommend 5
Comments Array
Submit your papers