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Grating-based X-ray Tomosynthesis on Biological Sample
Ran Zhang 1 #,Zhiqiang Chen 2 *,Li Zhang 1,Xiaolei Jiang 2,Hongxia Yin 1,Zhenchang Wang 2
1.Department of Engineering Physics, Tsinghua Universiy, 100084
2.Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing, 100084
*Correspondence author
#Submitted by
Subject:
Funding: National Natural Science Foundation of China (No.No. 10905031) , Specialized Research Fund for the Doctoral Program of Higher Education)
Opened online:12 June 2012
Accepted by: none
Citation: Ran Zhang,Zhiqiang Chen,Li Zhang.Grating-based X-ray Tomosynthesis on Biological Sample[OL]. [12 June 2012] http://en.paper.edu.cn/en_releasepaper/content/4479879
 
 
X-ray grating-based imaging can provide additional contrast mechanisms other than absorption, namely (differential) phase shift and small-angle scattering. For many biological samples which have poor absorption contrast, the (differential) phase shift and small-angle scattering contrast may provide useful information. Tomosynthesis is a three-dimensional reconstruction technique that aims to separate the overlapping structure of the object with a few projections from a limited angle. In this work, grating-based tomosynthesis with synchrotron radiation source has been performed. Tomosynthetic results using both analytical and iterative reconstruction methods have been compared. It is seen from the results that images reconstructed using iterative method with total variation constraint have better visual effect.
Keywords:grating-based imaging; reconstruction; tomosynthesis
 
 
 

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