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Genome restructuring for rebalancing in bacteria
Liu Guirong 1,Liu Weiqiao 2,He Xiaoyan 3,Zhao Gexin 3,Xu Guomin 3,Li Junqian 3,Deng Juan 3,Tang Jie 3,Qi Danni 4,Zhang Fengmin 4,Liu Shulin 1
1.Department of Microbiology, Peking University Health Science Center, Beijing, China; 2Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, AB, Canada; 3Department of Microbiology, Harbin Medical University, Harbin, China
2.Department of Microbiology and Infectious Diseases- University of Calgary
3.Department of Microbiology, Peking University Health Science Center, Beijing, China
4.Harbin Medical University, Harbin, China
*Correspondence author
#Submitted by
Subject:
Funding: 教育部博士点基金(No.20030001029)
Opened online:14 November 2006
Accepted by: none
Citation: Liu Guirong,Liu Weiqiao,He Xiaoyan.Genome restructuring for rebalancing in bacteria[OL]. [14 November 2006] http://en.paper.edu.cn/en_releasepaper/content/9565
 
 
Bacterial genome structure can be remarkably stable over extended periods of evolution, but may occasionally undergo a burst of rearrangement events. Evidence is accumulating in host-adapted Salmonella pathogens to demonstrate a correlation between genomic insertions and restructuring, supporting a hypothesis of genomic restructuring as a mechanism of topological rebalancing. These events may constitute a novel source of genomic variability that contributes to adaptive potential.
Keywords:S. typhi; Bacterial genome; Genomic rearrangement; Genomic evolution
 
 
 

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