Induced Pluripotent Stem (iPS) Cell：A novel potential resource for Hematopoietic Stem Cell Transplantation (HSCT)

WANG Jing; CHEN Jing; PAN Xiongfei; BA Kai; GE Yuehua; LIN Yunfeng

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Induced Pluripotent Stem (iPS) Cell：A novel potential resource for Hematopoietic Stem Cell Transplantation (HSCT)

WANG Jing 1 #,CHEN Jing 2,PAN Xiongfei 3,BA Kai 2,GE Yuehua 2,LIN Yunfeng 2 *

1.the State Key Laboratory of Oral Diseases, West China College of Stomatology, West China College of Stomatology, Sichuan University

2.the State Key Laboratory of Oral Diseases, West China College of Stomatology, West China College of Stomatology, Sichuan University, Chengdu, 610041

3.Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu 610041

*Correspondence author

#Submitted by

Subject:

Funding: the Specialized Research Fund for the Doctoral Program of Higher Education （No.20070610062）, National Natural Science Foundation of China （No.30801304, 81071273）

Opened online:30 December 2010

Accepted by: none

Citation: WANG Jing,CHEN Jing,PAN Xiongfei.Induced Pluripotent Stem (iPS) Cell：A novel potential resource for Hematopoietic Stem Cell Transplantation (HSCT)[OL]. [30 December 2010] http://en.paper.edu.cn/en_releasepaper/content/4400271

As a current procedure, hematopoietic stem cell transplantation (HSCT) has been applied for various blood diseases, such as leukemia and lymphoma. However, it sometimes causes significant immunological rejection, which may do harm to the recipients. Several researches have suggested that human iPS cells possess differentiation potentials to hematopoietic progenitor cells and lack of immunologic rejection. The hypothesis may be proposed that human iPS cells could be a novel potential resource for hematopoietic stem cell transplantation (HSCT). It is indicated that iPS cells will be a safer resource for research and clinic applications in future.

Keywords:Biomedical Engineering; Stem Cell; Induced Pluripotent Stem (iPS) Cell; Hematopoietic Stem Cell Transplantation (HSCT)

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