Differential evolution patterns in brain temperature in different ischemic tissues in Monkey Middle Cerebral Artery Occlusion Model

SUN Zhihua; Zhang Jing; CHEN Yingmin; ZHANG Xuejun; ZHANG Yunting; GUO Hong; YU Chunshui

Chinese︱Feedback︱Save this page

• Elaborating Academic Views 　　　　 • Exchanging Innovative Ideas
• Protecting Intellectual Properties 　　• Fast Sharing Science Papers

Sponsored by the Center for Science and Technology Development of the Ministry of Education
Supervised by Ministry of Education of the People's Republic of China

Home > Papers

Differential evolution patterns in brain temperature in different ischemic tissues in Monkey Middle Cerebral Artery Occlusion Model

SUN Zhihua 1 #,Zhang Jing 2,CHEN Yingmin 3,ZHANG Xuejun 2,ZHANG Yunting 2 *,GUO Hong 2,YU Chunshui 2

1.Department of Radiology , Tianjin Medical University General Hospital, Tianjin 300052

2.Department of Radiology , Tianjin Medical University General Hospital, Tianjin, 300052

3.Department of Radiology, The People Hospital of Hebei Province, 050005

*Correspondence author

#Submitted by

Subject:

Funding: National Doctoral Fund of Ministry of Education（No.No.20091202110006）

Opened online: 7 June 2012

Accepted by: none

Citation: SUN Zhihua,Zhang Jing,CHEN Yingmin.Differential evolution patterns in brain temperature in different ischemic tissues in Monkey Middle Cerebral Artery Occlusion Model[OL]. [ 7 June 2012] http://en.paper.edu.cn/en_releasepaper/content/4480417

Objectives: Brain temperature was elevated in acute ischemic stroke, especially in ischemic penumbra (IP). We try to investigate the dynamic evolution of brain temperature in different ischemic regions in monkey models. Methods: The middle cerebral artery occlusion (MCAO) and recanalization model was successfully established in 4 monkeys. Brain temperature of different ischemic regions was measured by Proton magnetic resonance spectroscopy (1H MRS), and then the evolution processes of brain temperature were compared among different ischemic regions. Results: The normal (baseline) brain temperature of monkey brain was 37.16℃. At artery occlusion stage, the mean brain temperature of ischemic tissue was 1.16℃higher than that of the baseline, however, this increase is region-dependent with 1.72℃ in IP, 1.08℃ in infarct core and 0.62℃ in oligemia region. After recanalization, the brain temperature of infarct core showed a pattern of an initially decrease accompanied by a following increase. However, the brain temperature of IP and oligemia region showed a monotonously and slowly decreased pattern. Conclusion: The infarct core and IP have different evolution patterns of brain temperature, which suggests that in vivo measurement of brain temperature could be help to identify whether ischemic tissue is survival.

Keywords:Ischemic stroke; brain temperature; ischemic penumbra; Magnetic Resonance Spectroscopy

For this paper

● PDF (0B)
● Revision 0 　　
● Print this paper
● Recommend this paper to a friend
● Add to my favorite list

Saved Papers

Please enter a name for this paper to be shown in your personalized Saved Papers list

Tags

Add yours

Related Papers

Statistics

PDF Downloaded	321
Bookmarked	0
Recommend	5
Comments	Array

Submit your papers

Alert Name:
Alerting to:
Authentication email will be sent to your email address in 24 hours
Frequency:
Email Message Format:	Plain text Graphical(HTML)

Complete the form below and we will recommend the selected titles to your friends on your behalf. * Indicates a required field.
Your name*:
Your email address*:
Recipient's name*:
Recipient's email address*:
(multiple recipient's names and email addresses should be separated with semicolons)
Your comments:	I thought you would find the page(s) useful.

Your name:
Your email address:
Recipient's name:
Recipient's email address:
(multiple recipient's names and email addresses should be separated with semicolons)
Your comments:	I thought you would find this page useful.

Disclaimer: This message was sent to your friend using the "Send it to a friend" facility on the Sciencepaper Online’ WWW site, http://www.paper.edu.cn/en. The Sciencepaper Online is not responsible for the content of this email, and anything said in this email does not necessarily reflect the Sciencepaper Online's views.

	Check out RSS, or use RSS reader to subscribe this item

Saved Papers