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Pd(II)-Catalysed Monoarylation of 2-Phenylpyridine N-Oxides with Iodobenzene in Water
Zhang Wei,Zhou Xiangge *
College of Chemistry, Sichuan University, Chengdu 610064
*Correspondence author
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Funding: Ministry of Education of China (No.no. 20120181110050)
Opened online:27 May 2016
Accepted by: none
Citation: Zhang Wei,Zhou Xiangge.Pd(II)-Catalysed Monoarylation of 2-Phenylpyridine N-Oxides with Iodobenzene in Water[OL]. [27 May 2016] http://en.paper.edu.cn/en_releasepaper/content/4691373
 
 
A Pd(II)-catalysed activation and arylation of C(sp2)-H bond directed by pyridine N-oxide in water is achieved with high regioselectivity to form monoarylated products in yields up to 91%. The wide substrate scope highlights the flexibility of the catalyst.The reaction mechanism is proposed.
Keywords:Organic Chemistry; Palladium; Catalysis; 2-Phenylpyridine N-Oxide; Water
 
 
 

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