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Contribution of glycerol on production of poly(γ-glutamic acid) in Bacillus subtilis NX-2
Qun Wu 1,Hong Xu 1 * #,Jinfeng Liang 2,Yaoi Jun 2
1.College of Life Science and Pharmacy, Nanjing University of Technology
2.College of Life Science and Pharmacy，Nanjing University of Technology
*Correspondence author
#Submitted by
Subject:
Funding: 973项目,国家自然科学基金,国家自然科学基金,江苏省研究生创新计划（No. 2003CB716004,20674038,20336010,）
Opened online: 4 January 2008
Accepted by: none
Citation: Qun Wu,Hong Xu,Jinfeng Liang.Contribution of glycerol on production of poly(γ-glutamic acid) in Bacillus subtilis NX-2[OL]. [ 4 January 2008] http://en.paper.edu.cn/en_releasepaper/content/17735
 
 
nGlycerol would stimulate the production of poly(γ-glutamic acid) (γ-PGA) and decrease its molecular weight in B. subtilis NX-2. The yield of γ-PGA increased from 26.7 to 31.7 g/l when 20 g/l glycerol was added in medium, and the molecular weight of γ-PGA could be regulated between 2.43×106 and 1.42×106 Da with glycerol concentration ranging from 0 to 60 g/l. The effect of glycerol on molecular weight of γ-PGA had never been reported, and it would be developed to be an approach for the regulation of microbial γ-PGA chain length
Keywords:B. subtilis NX-2, fermentation, glycerol, molecular weight, poly(γ-glutamic acid)
 
 
 

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