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Preparation, optical properties and cell staining of water soluble amine-terminated PAMAM G2.0-Au nanocomposites
Xia Jinlan * #,Fu Jindian,Nie Zhenyuan,Shen Li
School of Resources Processing and Bioengineering, Central South University
*Correspondence author
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Funding: none
Opened online:27 April 2005
Accepted by: none
Citation: Xia Jinlan,Fu Jindian,Nie Zhenyuan.Preparation, optical properties and cell staining of water soluble amine-terminated PAMAM G2.0-Au nanocomposites[OL]. [27 April 2005] http://en.paper.edu.cn/en_releasepaper/content/1949
 
 
he solution chemical and optical characteristics of formation of NH2-PAMAM G2.0-Au nanocomposites in the aqueous solution of amine-terminated polyamidoamine dendrimer G2.0 (NH2-PAMAM G2.0) under various mole ratios of Au(III)/PAMAM were studied by both UV-Vis spectrometry and fluorospectrometry. The NH2-PAMAM G2.0-Au nanocomposites, with a type of structure in which one Au nanoparticle was surrounded by several NH2-PAMAM dendrimers, emitted strong bluish violet fluorescence, and were uniform, water soluble and biocompatible as well as very stable in frozen conditions. The sizes of gold nanoparticles in the nanocomposites were about 2.5nm and decreased with increase of NH2-PAMAM G2.0 concentration. The NH2-PAMAM G2.0 played an important role in being as host or micro-reactor for Au(Ⅲ) before Au(Ⅲ) reduction and being as dispersant and stabilizer for gold nanoparticles after Au(Ⅲ) reduction. Preliminary experiments of cells staining to human embryonic lung fibroblast (HELF) cell lines s
Keywords:polyamidoamine dendrimer, nanocomposites, gold nanoparticles, optical properties, cell staining
 
 
 

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