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Copper-Catalyzed Highly Efficient Multicomponent Reactions:Synthesis of quinolin-2(1H)-imine
She Debing * #,Yang Mingyu,Hui Haohao,Zhao Qin,Chen Min,Huang Guosheng
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou
*Correspondence author
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Funding: none
Opened online: 6 May 2008
Accepted by: none
Citation: She Debing,Yang Mingyu,Hui Haohao.Copper-Catalyzed Highly Efficient Multicomponent Reactions:Synthesis of quinolin-2(1H)-imine[OL]. [ 6 May 2008] http://en.paper.edu.cn/en_releasepaper/content/21174
 
 
A variety of substituted quinolin-2(1H)-imine are prepared via a copper-catalyzed multicomponenet reaction of sulfonyl azides, terminal alkynes, and o-aminobenzaldehyde. First sulfonyl azides, alkynes under the copper catalysis condition build the intermediate, then o-aminobenzaldehyde dehydrogenation under Et3N condition and attact the intermediate to form the quinolin-2(1H)-imine.
Keywords:sulfonyl azides, alkynes, o-aminobenzaldehyde, multicomponent reactions
 
 
 

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