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Progess in the synthesis of chiral tetrahedroquinoline derivatives from asymmetric inverse electron-demand aza-Diels-Alder reaction
Xie Mingsheng 1,Lin Lili 1,Liu Xiaohua 1,Feng Xiaoming 2 * #
1.Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University
2.Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064
*Correspondence author
#Submitted by
Subject:
Funding: 高等学校博士学科点专项科研基金(No.20070610019)
Opened online: 9 October 2010
Accepted by: none
Citation: Xie Mingsheng,Lin Lili,Liu Xiaohua.Progess in the synthesis of chiral tetrahedroquinoline derivatives from asymmetric inverse electron-demand aza-Diels-Alder reaction[OL]. [ 9 October 2010] http://en.paper.edu.cn/en_releasepaper/content/4386893
 
 
Optically active tetrahydroquinoline derivatives have attracted considerable attention due to their important biological activities. For their construction, catalytic asymmetric inverse electron-demand aza-Diels-Alde reaction of N-arylimines with electron-rich alkenes (dienophiles) has been demonstrated to be one of the most powerful strategies. In this article, the progress of asymmetric catalytic inverse electron-demand aza-Diels-Alder is summarized according to the kind of the dienophiles. The future of the development of the reaction is also discussed.
Keywords:Organic chemistry; aza-Diels-Alder; inverse electron-demand; tetrahydroquinoline; alkene; asymmetric catalysis
 
 
 

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