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Objective To evaluate the changes of radiofrequency ablation coagulation region during real-time temperature monitoring by using transparent tissue-mimicking phantom contained polyacrylamide gel.
Materials and Methods A new urethra temperature monitoring catheter was manufactured with thermal mini-sensors. Put the urethra temperature monitoring catheter into the phantom made of polyacrylamide gel and bovine serum albumin. The phantom prepared with citrate buffer was used as temperature sensitive indicator. An electrode was inserted into the phantom vertically, 1 cm away from the temperature monitoring catheter. The parameters of coagulation lesions including the shapes, sizes, volumes and decenter ratios were evaluated by MRI imaging.
Results The coagulation region showing low signal region in the T2 image was clearer than high signal region showed in T1 image. Comparing to without temperature monitoring, the smaller coagulation region was observed during temperature monitoring. In addition, from the decenter ratios, the coagulation region seemed departed away from the electrode.
Conclusions The real-time temperature monitoring during radiofrequency ablation could affect the parameters of coagulation lesions including the shapes, sizes, volumes and decenter ratios. |
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Keywords:radiofrequency ablation; urethra; tissue-mimicking phantom; polyacrylamide gel; thermocouple |
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