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| Purpose To compare the clinical outcomes between thulium laser transurethral enucleation of the prostate (ThuLEP) and plasmakinetic bipolar resection of the prostate (PKRP) for treating benign prostatic hyperplasia (BPH) in a prospective randomized trial with 5 years of follow-up. Materials and methods 158 consecutive patients with BPH were randomized to either ThuLEP (n = 79) or PKRP (n = 79). All cases were evaluated preoperatively and part of these patients were evaluated at 3-5 years postoperatively by International Prostate Symptom Score (IPSS), quality of life score (QoL), maximum ?ow rate (Qmax) and postvoid residual urine volume (PVR). Results A total of 80 patients completed the 5-year follow-up. Each study arm showed no significant difference in preoperative parameters. Compared with PKRP, ThuLEP required longer operation time (65.4 vs 47.4 minutes, p = 0.022) but resulted in less haemoglobin decrease (0.15 vs 0.30 g/dL, p = 0.045). ThuLEP also needed less catheterization time (2.1 vs 3.5 days, p =0 .031), irrigated volume (12.4 vs 27.2 L, p = 0.022) and hospital stay (2.5 vs 4.6 days, p = 0.026). During the 60 months follow-up, both procedures demonstrated no significant difference in terms of Qmax, IPSS, PVR, and QoL. Conclusions Both ThuLEP and PKRP relieve lower urinary tract symptoms equally with high efficacy and safety. ThuLEP was statistically superior to PKRP in blood loss, catheterization time, irrigated volume and hospital stay, but inferior to PKRP in operation time. However, both procedures showed no significant difference in terms of Qmax, IPSS, PVR, and QoLS through the 60 months follow-up.) |
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| Keywords:BPH; TURP; PKRP; THULIUM LASER. |
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