Recent Advances in Organocatalytic Asymmetric Sulfa-Michael Reactions

YANG Yuting; ZHU Bo; JIANG Zhiyong

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Recent Advances in Organocatalytic Asymmetric Sulfa-Michael Reactions

YANG Yuting 1,ZHU Bo 1,JIANG Zhiyong 2 * #

1.Department of Pharmacy, Luohe Medical college, HeNan LuoHe 462000

2.Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Kaifeng, Henan, P. R. China, 475004

*Correspondence author

#Submitted by

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Funding: Specialized Research Fund for the Doctoral Program of Higher Education （No.20104103120002）, Supported by Science Foundation of Luohe Medical college （No.No.2013-S-LMC23）

Opened online:20 January 2014

Accepted by: none

Citation: YANG Yuting,ZHU Bo,JIANG Zhiyong.Recent Advances in Organocatalytic Asymmetric Sulfa-Michael Reactions[OL]. [20 January 2014] http://en.paper.edu.cn/en_releasepaper/content/4582212

The chiral sulfur-containing compounds have many utilities in numerous important areas. In the context, the research on the asymmetric reactions to construct chiral sulfur-containing compounds is always hot area in asymmetric chemistry. This short review summarizes organocatalytic asymmetric sulfa-Michael reactions, which belong to the most important protocol to access chiral sulfur-containing compounds. Two synthetic strategies are discussed, including direct sulfa-Michael addition to various activated alkenes and sulfa-Michael-involved cascade reactions

Keywords:chiral sulfur-containing; asymmetric reactions; synthetic strategies

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