Home > Papers

 
 
Intraocular Expression of Serum Amyloid A in Proliferative Diabetic Retinopathy
FENG Jing #,MA Yan,JIANG Yanrong *
Department of Ophthalmology, People’s Hospital, Peking University, & Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, 100044
*Correspondence author
#Submitted by
Subject:
Funding: 基金项目：高等学校博士学科点专项研究基金（No.20110001110042）
Opened online:24 July 2014
Accepted by: none
Citation: FENG Jing,MA Yan,JIANG Yanrong.Intraocular Expression of Serum Amyloid A in Proliferative Diabetic Retinopathy[OL]. [24 July 2014] http://en.paper.edu.cn/en_releasepaper/content/4604319
 
 
PURPOSE: Since serum amyloid A (SAA) has been reported to regulate angiogenesis, we searched for an association between SAA, as proinflammatory factors, and diabetic retinopathy (DR).METHODS: Enzyme-linked immunosorbent assay (ELISA) measured the concentration of SAA in vitreous fluid and plasma. Dual-color immunofluorescence staining and semiquantitative reverse transcription polymerase chain reaction examined the expression of SAA in the excised membranes. Multiplex bead assay measured the concentration of SAA in aqueous humor. RESULTS: The concentrations of SAA in vitreous, aqueous and plasma were significantly higher in the DR group than in the control group. CONCLUSIONS: SAA with the inflammatory process may be involved in the development of PDR. Local expression of SAA may exist in PDR.
Keywords:Ophthalmology; Diabetic retinopathy; Inflammatory factor; Serum amyloid A; Vitreous fluid; Aqueous humor.
 
 
 

For this paper
  • ● PDF (0B)
  • ● Revision 0 　　
  • ● Print this paper
  • ● Recommend this paper to a friend
  • ● Add to my favorite list

    Saved Papers

    Please enter a name for this paper to be shown in your personalized Saved Papers list

Tags
Add yours

Related Papers

Statistics
PDF Downloaded 108
Bookmarked 0
Recommend 5
Comments Array
Submit your papers