An investigation on synthesizing biocompatible ZnO nanocrystals

Han Zhou; Heng Chenglin; Yang Rong

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An investigation on synthesizing biocompatible ZnO nanocrystals

Han Zhou 1,Heng Chenglin 2 * #,Yang Rong 1

1.School of Physics, Key Laboratory of Cluster Science of Ministry of Education, Beijing Institute of Technology, Beijing 100081

2. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190

*Correspondence author

#Submitted by

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Funding: Specialized Research Fund for the Doctoral Program of Higher Education (SRFDP) （No.20111101120021）

Opened online: 3 December 2015

Accepted by: none

Citation: Han Zhou,Heng Chenglin,Yang Rong.An investigation on synthesizing biocompatible ZnO nanocrystals[OL]. [ 3 December 2015] http://en.paper.edu.cn/en_releasepaper/content/4665113

We have synthesized aminopropyl triethoxysilane (APTES) decorated zinc oxide (ZnO) nanocrystals, and investigated their optical property and cytotoxicity properties. Transmission electron microscopy, dynamic light scattering and X-ray diffraction analysis, demonstrated that crystalline ZnO nanoparticles had been synthesized by using sol-gel method with an average size of 8 nm. The APTES decorated ZnO nanocrystals showed a stable and broad emission band with peak position at around 540-550 nm under excitation of a 330 nm Xe-lamp line. Cell viability analysis indicated that the decorated ZnO nanocrystals had not significant influence on the cervical carcinoma cell proliferation until the concentration was up to of 20μg/mL.)

Keywords:ZnO nanocrystals; sol-gel method; APTES decoration; biocompatibility

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