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	1. The Preparation of Core/Shell Nanofibers by Electrospinning: Applications in Tissue Engineering and Drug Delivery
	Yang Guorui,Yan wei
	Pharmacy 18 June 2010
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:Electrospinning is a simple and versatile technique that can generate continuous fibers with diameters ranging from a few micrometers to a few nanometers. In the recent years, much progress has occurred in electrospinning. A myriad of functional polymers have been electrospun, and many new nanostructures such as hollow, core/shell and porous fibers have been obtained. This paper highlights the usage of electrospinning in the fabrication of core/shell nanofibers, as well as the efforts made to improve their application in tissue engineering and drug delivery. The studies presented indicate that core/shell nanofibers afford the opportunity to engineer scaffolds with topography on a micro to nanoscale, and a high porosity akin to that found in the natural extracellular matrix (ECM). Such nanofibers can provide sustained drug release as well as mitigate the initial burst release that occurs with traditional polymer/drug blends.
	TO cite this article:Yang Guorui,Yan wei. The Preparation of Core/Shell Nanofibers by Electrospinning: Applications in Tissue Engineering and Drug Delivery[OL].[18 June 2010] http://en.paper.edu.cn/en_releasepaper/content/4376582

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