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1. Protective effect of total glycoside from Ligustrum lucidum on concanavalin A-induced liver injury in mice | |||
YANG Nianyun,GUO Jianming,YU Li | |||
Traditional Chinese Medicine and Pharmacology 15 January 2014 | |||
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Abstract:Objective: To investigate the protective effect of total glycoside extract (TGE) from Ligustrum lucidum on concanavalin A-induced liver injury in mice. Methods: Con A injection into the tail vein caused hepatitis mice model via an intragastric feeding and TGE was meanwhile intervened, while the mice in control group were fed normal diet. At the end of experiments, all the mice were sacrificed to analyze serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6) levels. Pathological changes of hepatic tissues were observed under microscope. Results: Compared to model group, serum ALT, AST, TNF-a and IL-6 levels exhibited an obvious reduction in TGE intervened mice (P<0.05). Conclusion: TGE has a significant preventive effect on Con A-induced hepatitis in mice, which can inhibit pro-inflammatory cytokines, relieve the peroxidation injury and improve liver function. | |||
TO cite this article:YANG Nianyun,GUO Jianming,YU Li. Protective effect of total glycoside from Ligustrum lucidum on concanavalin A-induced liver injury in mice[OL].[15 January 2014] http://en.paper.edu.cn/en_releasepaper/content/4582559 |
2. Research advance of safflower on chemical composition | |||
Li Junfu,Yin Rongli,Wei Juan,Li Xiaoyi,Luo Yan | |||
Traditional Chinese Medicine and Pharmacology 22 September 2008 | |||
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Abstract:Safflower,as a plant of Carthamus L.in compositae,is one of blood-activating and stasis-eliminating Chinese medicines,Safflower Yellow is mainly its active component. Modern studies shows that Safflower has significant effects on Cardiocerebral Vascular Diseases This text overviews the reseach advance of safflower from chemical composition, pharmacologic action,pharmacokineticcs and toxicology respectively. | |||
TO cite this article:Li Junfu,Yin Rongli,Wei Juan, et al. Research advance of safflower on chemical composition[OL].[22 September 2008] http://en.paper.edu.cn/en_releasepaper/content/24204 |
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