Authentication email has already been sent, please check your email box: and activate it as soon as possible.
You can login to My Profile and manage your email alerts.
If you haven’t received the email, please:
|
|
There are 1 papers published in subject: > since this site started. |
Results per page: |
Select Subject |
Select/Unselect all | For Selected Papers |
Saved Papers
Please enter a name for this paper to be shown in your personalized Saved Papers list
|
1. The synergistic anti-tumor effects of evodiamine based on animal model experiments: a systematic review and meta analysis | |||
Zheng He,Jiang Li,Pang yunqing,Lv Siyi,Lin Liqi,Wang Jing | |||
Traditional Chinese Medicine and Pharmacology 13 April 2022 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:Evodiamine (EVO) is an alkaloid extracted from the dried and nearly ripe fruits of Euodia rutaecarpa used as an anti-cancer, anti-inflammatory and anti-obesity agent. However, robust evidence of preclinical experiments has been lacking so far. As a consequence, a systematic review and meta-analysis was conducted to assess the anti-tumor effect of evodiamine combined therapy. The search engine and electronic databases includes PubMed, Scopus, China Knowledge Resource Integrated Database (CNKI) and SinoMed. Stata 15.0 was used for data extraction. Tumor volume and tumor weight were evaluate at a 95% confidence level using random effects model. Begg\'s test and funnel plot were used for the evaluation of publication bias. Sensitivity analysis is used to investigate the stability of results.A total of 7 studies and 108 animals were included. Overall, EVO reduced tumor volume(SMD=-25.64,95% CI: -5.77 -3.13,I2=92.5%, P<0.05) and tumor weight(SMD=-8.91,95% CI: -16.37, -1.44,I2=94.1%, P<0.05). As a result, EVO combined therapy appears to be more effective compared with monotherapy. Moreover, EVO has a potential to alleviate the toxicity of chemotherapeutic agents, which increases the translatability to the clinical situation. | |||
TO cite this article:Zheng He,Jiang Li,Pang yunqing, et al. The synergistic anti-tumor effects of evodiamine based on animal model experiments: a systematic review and meta analysis[OL].[13 April 2022] http://en.paper.edu.cn/en_releasepaper/content/4757287 |
Select/Unselect all | For Selected Papers |
Saved Papers
Please enter a name for this paper to be shown in your personalized Saved Papers list
|
Results per page: |
About Sciencepaper Online | Privacy Policy | Terms & Conditions | Contact Us
© 2003-2012 Sciencepaper Online. unless otherwise stated