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1. Numerical simulation on the dynamics and oxygen uptake of red blood cells | |||
Zhijun Tan,P.G. Jayathilake | |||
Biology 11 November 2014 | |||
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Abstract:Red blood cells (RBCs) are very important due to their role of oxygen transport from lungs. As the malaria parasite grows in the malaria-infected red blood cells (IRBCs), the properties of the cells change. In the present work, the oxygen uptake by RBCs and IRBCs at the pulmonary capillaries is simulated using a numerical technique based on the two-dimensional immersed interface method. The results for the oxygen uptake by a stationary single RBC have fair agreements with the previously reported results. The numerical results show that the malaria infection could significantly cause deterioration on the oxygen uptake by red blood cells. The results also suggest that the oxygen uptake by individual stationary RBC/IRBC would not be significantly affected by the neighboring cells provided the separation distance is about the dimension of the cell. ????? | |||
TO cite this article:Zhijun Tan,P.G. Jayathilake. Numerical simulation on the dynamics and oxygen uptake of red blood cells[OL].[11 November 2014] http://en.paper.edu.cn/en_releasepaper/content/4618192 |
2. The activity of myosin II motor and the volume of actin filament cooperatively regulate cytokinesis of | |||
Yang Fang,An Meiwen,Li Xiaona,Wang Li | |||
Biology 25 March 2010 | |||
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Abstract:The coordination of different cytoskeletons is an important factor in maintaining normal physiological and biochemical characteristics. In this study, normal rat kidney (NRK) cells in cytokinesis were treated with cytoskeleton inhibitors including cytochalasin D (CD), colchicine (COLC) oblebbistatin (myosin II motor activity inhibitor ). These inhibitors were released at the whole region and the localized region in two phases of cytokinesis. The influences were analyzed. It was showed that the roles of cytoskeleton inhibitors to cytokinesis were complex, for different treatment of inhibiotors corresponding to different results. The study indicated that the interaction in actin and the activity of myosin II motor is vital to cell shape and operation in every stages of cytokinesis. | |||
TO cite this article:Yang Fang,An Meiwen,Li Xiaona, et al. The activity of myosin II motor and the volume of actin filament cooperatively regulate cytokinesis of [OL].[25 March 2010] http://en.paper.edu.cn/en_releasepaper/content/41129 |
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