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1. Modeling for Cellular Responding Radiotherapy based on a Gene Regulatory Networks | |||
Qi jinpeng,Shao shihuang,Ding yongsheng | |||
Information Science and System Science 21 September 2009 | |||
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Abstract:To simulate the investigation of the cellular responding acute ion radiation (IR) under radiotherapy, by using the methods with the system biology and cyber-biology, a model of P53 stress response networks is proposed at single cell level. Meanwhile, the dynamic processes of DNA damage transferring, the complicated regulating among vital genes, as well as the degradation of toxins are presented during radiotherapy,. Especially, the plausible outcomes of cellular responding acute IR are predicted under different IR dose domains. Furthermore, some meaningful instructions in selecting the optimal IR dose and therapy time are provided prior to clinical radiotherapy. | |||
TO cite this article:Qi jinpeng,Shao shihuang,Ding yongsheng. Modeling for Cellular Responding Radiotherapy based on a Gene Regulatory Networks[OL].[21 September 2009] http://en.paper.edu.cn/en_releasepaper/content/35341 |
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