Authentication email has already been sent, please check your email box: and activate it as soon as possible.
You can login to My Profile and manage your email alerts.
If you haven’t received the email, please:
|
|
There are 1 papers published in subject: > since this site started. |
Results per page: |
Select Subject |
Select/Unselect all | For Selected Papers |
Saved Papers
Please enter a name for this paper to be shown in your personalized Saved Papers list
|
1. The motility and invasion of tumor cell and its association with Fascin | |||
Ma Gui,Li WeiPing | |||
Basic Medicine 11 June 2010 | |||
Show/Hide Abstract | Cite this paper︱Full-text: PDF (0 B) | |||
Abstract:In the progression of the cancer, carcinoma cells migrate away from primary tumors, traverse to basement membrane and ECM, overcome the cell-cell and cell-ECM adhesions, invade surrounding tissue, and come into the metastases through lymphatic and/or blood system .Of all these processes, the acquisition and increase of cell motile and invasive properties play a crucial role in the neoplastic progression. Fascin, as an Actin-bundling protein, is prevalently considered to induce specific morphological features of membrane protrusion, as well as the changes of cell adhesion and cell interactions, and ultimately enhance the cell motility for subsequent invasion and metastases, which is significantly associated with bad prognosis. Therefore, fascin over-expression is proposed to be a novel biomarker to provide effective early diagnosis for potentially aggressive tumors or be used to develop therapeutic strategies that can arrest invasion and even metastases. | |||
TO cite this article:Ma Gui,Li WeiPing. The motility and invasion of tumor cell and its association with Fascin[OL].[11 June 2010] http://en.paper.edu.cn/en_releasepaper/content/4376011 |
Select/Unselect all | For Selected Papers |
Saved Papers
Please enter a name for this paper to be shown in your personalized Saved Papers list
|
|
Results per page: |
About Sciencepaper Online | Privacy Policy | Terms & Conditions | Contact Us
© 2003-2012 Sciencepaper Online. unless otherwise stated