Chinese︱Feedback︱Save this page

Login︱Register

• Elaborating Academic Views 　　　　 • Exchanging Innovative Ideas
• Protecting Intellectual Properties 　　• Fast Sharing Science Papers

Sponsored by the Center for Science and Technology Development of the Ministry of Education
Supervised by Ministry of Education of the People's Republic of China

Home > Papers > Organic-Chemistry

There are 14 papers published in subject: > since this site started.

Results per page:

14 Total, 2 Pages | 1 2 Next > Last >>

Select Subject

All (8830)

Agronomy (158)

Animal Husbandry,... (64)

Aquatic Science (16)

Astronomy (36)

Aviation (22)

Basic Medicine (184)

Biology (504)

Chemical Engineering (103)

Chemistry (635)

Civil and Archite... (105)

Clinical Medicine (236)

Computer Science ... (924)

Dynamic and Elect... (121)

Earth Science (119)

Economics (67)

Education (31)

Electrics, Commun... (927)

Energy Science an... (67)

Engineering and T... (15)

Environmental Sci... (140)

Food Science and ... (63)

Forestry (36)

Hydraulic Enginee... (40)

Mechanics (240)

Metallurgical Eng... (32)

Mine Engineering ... (38)

Nuclear Science a... (21)

Pharmacy (98)

Physics (920)

Preventive Medici... (37)

Psychology (20)

Security Science ... (17)

Sports Science (6)

Surveying and Map... (15)

Textile Science a... (16)

Traditional Chine... (56)

Transportation En... (57)

Third-level Subject

Bioorganic Chemistry(6)
Elementary Organic Chemis...(5)
Organic Chemistry of Natu...(1)
Organic Photochemistry(5)
Organic Solid Chemistry(2)
Organic Synthesis Chemistry(13)
Other Subjects of Organic...(2)
Physical Organic Chemistr...(3)

Rank

Results per page:

14 Total, 2 Pages | 1 2 Next > Last >>

Alert Name:
Alerting to:
Authentication email will be sent to your email address in 24 hours
Frequency:
Email Message Format:	Plain text Graphical(HTML)

Complete the form below and we will recommend the selected titles to your friends on your behalf. * Indicates a required field.
Your name*:
Your email address*:
Recipient's name*:
Recipient's email address*:
(multiple recipient's names and email addresses should be separated with semicolons)
Your comments:	I thought you would find the page(s) useful.

Your name:
Your email address:
Recipient's name:
Recipient's email address:
(multiple recipient's names and email addresses should be separated with semicolons)
Your comments:	I thought you would find this page useful.

Disclaimer: This message was sent to your friend using the "Send it to a friend" facility on the Sciencepaper Online’ WWW site, http://www.paper.edu.cn/en. The Sciencepaper Online is not responsible for the content of this email, and anything said in this email does not necessarily reflect the Sciencepaper Online's views.


	1. Mechanism Study of Iron(Ⅲ)-Porphyrin Catalyzed Cycloproanation of Aromatic Alkene with Trifluoroethylamine Hydrochloride
	Xiao Jiang,Liu Qiang
	Chemistry 31 May 2020
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:A substrate scopes of cyclopropanation has been expanded with trifluoroethylamine hydrochloride catalyzed by TPFPPFeCl under a user-friendly condition. Trifluoromethyl-substituted cyclopropanes were generated with high diastereoselectivity and yield, employing styrene derivatives and other heterocyclic alkene as substrates. Moreover, mechanism study shows TPFPP(NO) is the most important reaction intermediate which has not been reported in other metalloporphyrin-catalyzed cyclopropanation reactions.
	TO cite this article:Xiao Jiang,Liu Qiang. Mechanism Study of Iron(Ⅲ)-Porphyrin Catalyzed Cycloproanation of Aromatic Alkene with Trifluoroethylamine Hydrochloride[OL].[31 May 2020] http://en.paper.edu.cn/en_releasepaper/content/4752267


	2. Total Synthesis of Mangiferin, Homomangiferin, and Neomangiferin
	WEI Xiong,LIANG Danlin,WANG Qing,MENG Xiangbao,LI Zhongjun
	Chemistry 26 July 2016
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:Total synthesis of mangiferin, homomangiferin, and neomangiferin, three C-glycosyl xanthone natural products with a wide spectrum of pharmacological effects, have been achieved starting from 2,3,4,6-tetra-O-benzyl-glucopyranose. The key steps involve a stereoselective Lewis acid promoted C-glycosylation of protected phloroglucinol with tetrabenzylglucopyranosyl acetate and a highly regioselective base-induced cyclization for the construction of the core xanthone skeleton.
	TO cite this article:WEI Xiong,LIANG Danlin,WANG Qing, et al. Total Synthesis of Mangiferin, Homomangiferin, and Neomangiferin[J].

Saved Papers

Saved Papers


	3. Comparative Studies of Three Synthetic Routes of Enzymatic Multicomponent Reactions (MCRs) for Strongly Fluorescent Spirooxazino Derivatives
	CHEN Xiaoyang,LIN Xianfu
	Chemistry 03 December 2015
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:Enzymatic multicomponent reactions are very powerful for complicated organic synthesis with environmental friendly, highly efficient and selective characters. Herein, we designed and compared three routes of enzymatic MCRs for simple and efficient synthesis of complicated spirooxazinos derivatives, and one more efficient synthesis methodology for the target compounds than before was developed. Reaction conditions such as enzymes, enzyme concentration, amides and ratio of substrates were screened, and 15 spirooxazino derivatives were obtained in moderate to good yield. All of these novel spirooxazinos have strong fluorescence emission ability and high quantum yields, providing great application potential in photoactive materials. Furthermore, particularly interesting is that chiral spirooxazino could also be obtained through a developed two-enzymatic MCRs process in one pot.
	TO cite this article:CHEN Xiaoyang,LIN Xianfu. Comparative Studies of Three Synthetic Routes of Enzymatic Multicomponent Reactions (MCRs) for Strongly Fluorescent Spirooxazino Derivatives[OL].[ 3 December 2015] http://en.paper.edu.cn/en_releasepaper/content/4666965


	4. One-pot synthesis of benzothiazolones from 2-haloanilines, potassium sulfide and N,N-dimethylformamide
	Li Zhengkai,Li Xiaoya,Zhou Xiangge
	Chemistry 09 July 2015
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:Benzothiazolones represent an important class of compounds found in medicines and pesticides. The traditional synthetic methods to prepare of benzothiazolones usually suffered from the limitation of commercially available starting materials such as substituted o-aminothiophenols, toxic carbonyl sources or multiple steps. In this paper, an efficient Cu-catalyzed one-pot synthesis of benzothiazolones directly from easily available 2-haloanilines, potassium sulfide and N,N-dimethylformamide (DMF) as strating materials has been developed. In this protocol, C-S and C-N bond formation occurs during reactions with yields up to 87% after optimization of reaction conditions, which was CuSO4 (10 mol%), 2,2'-bipyridine (10 mol%), and NaOH (3 equiv) at 120 C for 18 h without inert atmosphere. Electron-donating groups seemed to be beneficial to the catalysis than electron-withdrawing groups, which indicated the electron-donating groups would benefit the nucleophilic attack during reaction. The mechanism studies revealed that the carbonyl group of product came from DMF.
	TO cite this article:Li Zhengkai,Li Xiaoya,Zhou Xiangge. One-pot synthesis of benzothiazolones from 2-haloanilines, potassium sulfide and N,N-dimethylformamide[OL].[ 9 July 2015] http://en.paper.edu.cn/en_releasepaper/content/4649429


	5. Synthesis and antitumor activities of novel α-aminophosphonates from alizarin
	Gui-yang Yao,Heng-shan Wang
	Chemistry 14 October 2014
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:The synthesis of new α-aminophosphonates derivatives containing alizarin (6a-6f, 7a-7h) moieties is described. Their inhibitory activities against the NCI-H460, Hct-116, 803, A549 and KB human cancer cell lines were estimated using MTT assay in vitro. The screening results revealed that many compounds exhibited moderate to high levels of antitumor activities against the tested cancer cell lines and that most demonstrated more potent inhibitory activities compared with the commercial anticancer drug 5-fluorouracil. The mechanism of compound 7g was preliminarily investigated by Hoechst 33258 staining, JC-1 mitochondrial membrane potential staining , which indicated that the compound 7g induced apoptosis inNCI-H460 cancer cells.
	TO cite this article:Gui-yang Yao,Heng-shan Wang. Synthesis and antitumor activities of novel α-aminophosphonates from alizarin[OL].[14 October 2014] http://en.paper.edu.cn/en_releasepaper/content/4613184


	6. Synthesis of Cyclohexanone-formaldehyde　Resin Catalyzed by Rehydrated Mg-Al Hydrotalcite
	Yang Guo,Jiang Junqing,Zhang Yanwu
	Chemistry 28 February 2014
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:Cyclohexanone-formaldehyde resin (CFR) was synthesized over rehydrated Mg-Al hydrotalcite (HT). Therein, Mg-Al HT was rehydrated from Mg-Al HT of good crystallinity using a liquid method. Rehydrated Mg-Al HT (HT-r) shows good catalytic activity for aldol condensation. In the synthesis of CFR catalyzed by HT-r, hexadecyl trimethyl ammonium bromide (CTAB) as a phase transfer catalyst was introduced to enhance the mass transfer. Both higher temperature and longer reaction time are preferable to increase the molecular weight of CFR. Though the catalytic activity of HT-r decreases as the reutilization cycle increases, the deactivated HT-r can be easily regenerated upon calcining and rehydrating.
	TO cite this article:Yang Guo,Jiang Junqing,Zhang Yanwu. Synthesis of Cyclohexanone-formaldehyde　Resin Catalyzed by Rehydrated Mg-Al Hydrotalcite[OL].[28 February 2014] http://en.paper.edu.cn/en_releasepaper/content/4587728


	7. Solubilities of 3,3'-[1,2-ethanediylbis (oxy-2,1-ethanediyl)]- bis[1-methyl- imidazolium] bis(hexafluorophosphate) in Dimethyl Formamide + Water
	GuoJiarong,Zhuang Linghua,WangYan,SunJie,WangGuowei
	Chemistry 16 January 2014
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:The chemical structure of a new gemini dicationic imidazolium ionic liquid, 3,3'-[1,2-ethanediylbis (oxy-2,1-ethanediyl)]- bis[1-methyl- imidazolium]- bis(hexafluorophosphate) ([C6O2(mim)2][PF6]2) was established by 1HNMR. Thermal stability of ([C6O2(mim)2][PF6]2) was studied with Differential scanning calorimetry (DSC) and thermogravimetry analyses (TG).Using a laser monitoring observation technique at atmospheric pressure, the solubilities of ([C6O2(mim)2][PF6]2) in a dimethyl formamide (DMF) + water binary solvent mixture had been measured from (285.65 to 326.55)K. The experimental data was correlated with the modified Apelblat equation and measured up to experimental data. And the average relative errors σ were all less than 0.30 %, the root-mean-square deviations were all less than 0.30.
	TO cite this article:GuoJiarong,Zhuang Linghua,WangYan, et al. Solubilities of 3,3'-[1,2-ethanediylbis (oxy-2,1-ethanediyl)]- bis[1-methyl- imidazolium] bis(hexafluorophosphate) in Dimethyl Formamide + Water[OL].[16 January 2014] http://en.paper.edu.cn/en_releasepaper/content/4582544


	8. Synthesis and crystal structure of tert-butyl 4-(3-phenylthioureido)piperidine-1-carboxylate
	Xiao-Hui Hu,Yu-Rui Gu,Yun Zuo,Xing Guo,Rui-Qin Fang
	Chemistry 20 August 2013
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:In this paper, we have synthesized tert-butyl 4-(3-phenylthioureido)piperidine-1-carboxylate by reacting isothiocyanatobenzene and 4-Amino-1-Boc-piperidine. The structure of title compound was confirmed by elemental analysis, ESI-MS spectrum and X-ray single crystal determination. The chain structure of title compound is formed by intramolecular N-H...O, N-H...S, C-H...O and intermolecular C-H...S hydrogen bonds.
	TO cite this article:Xiao-Hui Hu,Yu-Rui Gu,Yun Zuo, et al. Synthesis and crystal structure of tert-butyl 4-(3-phenylthioureido)piperidine-1-carboxylate[OL].[20 August 2013] http://en.paper.edu.cn/en_releasepaper/content/4556093


	9. Synthesis and photophysical properties of NIR-emitting neodymium (III)-complexes containing fluorene and carbazole functionalized phenanthroline
	Liu Yu,He Juan,Xing Kongqiang,Zhu Weiguo,Wang Yafei
	Chemistry 16 December 2012
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:Three novel neodymium (III) complexes of (G1G2FuPhen)Nd(TTA)3 with 2-thenoyltrifluoroacetone (TTA) ligand served as main sensitizers, and fluorene and/or carbazole-functionalized phenanthroline as the synergistic ligand were synthesized and characterized by elemental analysis, infrared spectroscopy and thermal analyses. These neodymium (III) complexes presented better thermal stability, and similar UV-vis absorption and photoluminescence spectra in dichloromethane. Two intense UV-vis absorption bands at around 272 nm and 343 nm, Upon excitation at the maximum absorption of the complexes, they all show the characteristic near-infrared (NIR) luminescence at about 880, 1060, 1330 nm of the corresponding Nd3+ ions, which is due to ef?cient energy transfer from the ligands to the central Nd3+ ions via an antenna effect. Moreover, the in?uence of ligands on the luminescence properties of the complexes is further discussed.
	TO cite this article:Liu Yu,He Juan,Xing Kongqiang, et al. Synthesis and photophysical properties of NIR-emitting neodymium (III)-complexes containing fluorene and carbazole functionalized phenanthroline[OL].[16 December 2012] http://en.paper.edu.cn/en_releasepaper/content/4504974


	10. Structural and functional insights into polymorphic enzymes of cytochrome P450 2C8
	Jiang Hualin,Tan Xiangshi
	Chemistry 28 September 2011
	Show/Hide Abstract \| Cite this paper︱Full-text: PDF (0 B)

	Abstract:The cytochrome P450 (CYP) superfamily plays a key role in the oxidative metabolism of a wide range of drugs and exogenous chemicals. CYP2C8 is the principal enzyme responsible for the metabolism of the anti-cancer drug paclitaxel in the human liver. Nearly all previous works about polymorphic variants of CYP2C8 were focused on unpurified proteins, either cells or human liver microsomes; therefore their structure-function relationships were unclear. In this study, two polymorphic enzymes of CYP2C8 (CYP2C8.4 (I264M) and CYP2C8 P404A) were expressed in E. coli and purified. Metabolic activities of paclitaxel by the two purified polymorphic enzymes were observed. The activity of CYP2C8.4 was 25% and CYP2C8 P404A was 30% of that of WT CYP2C8, respectively. Their structure-function relationships were systematically investigated for the first time. Paclitaxel binding ability of CYP2C8.4 increased about two times while CYP2C8 P404A decreased about two times than that of WT CYP2C8. The two polymorphic mutant sites of I264 and P404, located far from active site and substrate binding sites, significantly affect heme and/or substrate binding. This study indicated that two important nonsubstrate recognition site (SRS) residues of CYP2C8 are closely related to heme binding and/or substrate binding. This discovery could be valuable for explaining clinically individual differences in the metabolism of drugs and provides instructed information for individualized medication.
	TO cite this article:Jiang Hualin,Tan Xiangshi. Structural and functional insights into polymorphic enzymes of cytochrome P450 2C8[OL].[28 September 2011] http://en.paper.edu.cn/en_releasepaper/content/4444533

	Check out RSS, or use RSS reader to subscribe this item